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DGCR2-CLTCL1 Fusion FISH Probe

The DGCR2-CLTCL1 Fusion FISH Probe is used to confirm a fusion of the DGCR2 and CLTCL1 genes. The fusion of the DGCR2 and CLTCL1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DGCR2-CLTCL1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-RERE 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-REOR 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-REGO 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-REGR 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-REAQ 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-ORRE 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-OROR 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-ORGO 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-ORAQ 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-GORE 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-GOOR 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-GOGO 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-GOGR 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-GOAQ 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-GRRE 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-GROR 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-GRGO 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-GRGR 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-GRAQ 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-AQRE 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-AQOR 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-AQGO 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-AQGR 20 (40 μL) 200 μL
DGCR2-CLTCL1-20-AQAQ 20 (40 μL) 200 μL

CLTCL1 Gene Summary

This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Gene Name: Clathrin Heavy Chain Like 1

Chromosome: CHR22: 19166986 -19279239

Locus: 22q11.21

DGCR2 Gene Summary

Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Gene Name: DiGeorge Syndrome Critical Region Gene 2

Chromosome: CHR22: 19023794 -19109967

Locus: 22q11.21

Gene Diseases

The DGCR2 CLTCL1 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.