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DGCR2-IRX4 Fusion FISH Probe

The DGCR2-IRX4 Fusion FISH Probe is used to confirm a fusion of the DGCR2 and IRX4 genes. The fusion of the DGCR2 and IRX4 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DGCR2-IRX4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DGCR2-IRX4-20-RERE 20 (40 μL) 200 μL
DGCR2-IRX4-20-REOR 20 (40 μL) 200 μL
DGCR2-IRX4-20-REGO 20 (40 μL) 200 μL
DGCR2-IRX4-20-REGR 20 (40 μL) 200 μL
DGCR2-IRX4-20-REAQ 20 (40 μL) 200 μL
DGCR2-IRX4-20-ORRE 20 (40 μL) 200 μL
DGCR2-IRX4-20-OROR 20 (40 μL) 200 μL
DGCR2-IRX4-20-ORGO 20 (40 μL) 200 μL
DGCR2-IRX4-20-ORAQ 20 (40 μL) 200 μL
DGCR2-IRX4-20-GORE 20 (40 μL) 200 μL
DGCR2-IRX4-20-GOOR 20 (40 μL) 200 μL
DGCR2-IRX4-20-GOGO 20 (40 μL) 200 μL
DGCR2-IRX4-20-GOGR 20 (40 μL) 200 μL
DGCR2-IRX4-20-GOAQ 20 (40 μL) 200 μL
DGCR2-IRX4-20-GRRE 20 (40 μL) 200 μL
DGCR2-IRX4-20-GROR 20 (40 μL) 200 μL
DGCR2-IRX4-20-GRGO 20 (40 μL) 200 μL
DGCR2-IRX4-20-GRGR 20 (40 μL) 200 μL
DGCR2-IRX4-20-GRAQ 20 (40 μL) 200 μL
DGCR2-IRX4-20-AQRE 20 (40 μL) 200 μL
DGCR2-IRX4-20-AQOR 20 (40 μL) 200 μL
DGCR2-IRX4-20-AQGO 20 (40 μL) 200 μL
DGCR2-IRX4-20-AQGR 20 (40 μL) 200 μL
DGCR2-IRX4-20-AQAQ 20 (40 μL) 200 μL

DGCR2 Gene Summary

Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Gene Name: DiGeorge Syndrome Critical Region Gene 2

Chromosome: CHR22: 19023794 -19109967

Locus: 22q11.21

IRX4 Gene Summary

The Iroquois Homeobox 4 (IRX4) gene is located on chr5 :1877540-1882880 at 5p15.33.

Gene Name: Iroquois Homeobox 4

Chromosome: CHR5: 1877540 -1882880

Locus: 5p15.33

Gene Diseases

The DGCR2 IRX4 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.