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DNAJC6-PDE1C Fusion FISH Probe

The DNAJC6-PDE1C Fusion FISH Probe is used to confirm a fusion of the DNAJC6 and PDE1C genes. The fusion of the DNAJC6 and PDE1C genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DNAJC6-PDE1C-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-RERE 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-REOR 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-REGO 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-REGR 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-REAQ 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-ORRE 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-OROR 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-ORGO 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-ORAQ 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-GORE 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-GOOR 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-GOGO 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-GOGR 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-GOAQ 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-GRRE 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-GROR 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-GRGO 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-GRGR 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-GRAQ 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-AQRE 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-AQOR 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-AQGO 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-AQGR 20 (40 μL) 200 μL
DNAJC6-PDE1C-20-AQAQ 20 (40 μL) 200 μL

PDE1C Gene Summary

This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]

Gene Name: Phosphodiesterase 1C

Chromosome: CHR7: 31792631 -32338383

Locus: 7p14.3

DNAJC6 Gene Summary

DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008]

Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member C6

Chromosome: CHR1: 65730429 -65881552

Locus: 1p31.3

Gene Diseases

The DNAJC6 PDE1C Fusion has been associated with the following diseases:

Disease Name
Thyroid Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.