DNM2-ARHGEF7 Fusion FISH Probe
The DNM2-ARHGEF7 Fusion FISH Probe is used to confirm a fusion of the DNM2 and ARHGEF7 genes. The fusion of the DNM2 and ARHGEF7 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DNM2-ARHGEF7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-RERE | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-REOR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-REGO | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-REGR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-OROR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-GORE | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-GROR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGEF7-20-AQAQ | 20 (40 μL) | 200 μL |
|
DNM2 Gene Summary
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
Gene Name: Dynamin 2
Chromosome: CHR19: 10828728 -10942586
Locus: 19p13.2
ARHGEF7 Gene Summary
This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Mar 2016]
Gene Name: Rho Guanine Nucleotide Exchange Factor 7
Chromosome: CHR13: 111767623 -111947542
Locus: 13q34
Gene Diseases
The DNM2 ARHGEF7 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|