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DNMBP-TPTE2 Fusion FISH Probe

The DNMBP-TPTE2 Fusion FISH Probe is used to confirm a fusion of the DNMBP and TPTE2 genes. The fusion of the DNMBP and TPTE2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DNMBP-TPTE2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DNMBP-TPTE2-20-RERE 20 (40 μL) 200 μL
DNMBP-TPTE2-20-REOR 20 (40 μL) 200 μL
DNMBP-TPTE2-20-REGO 20 (40 μL) 200 μL
DNMBP-TPTE2-20-REGR 20 (40 μL) 200 μL
DNMBP-TPTE2-20-REAQ 20 (40 μL) 200 μL
DNMBP-TPTE2-20-ORRE 20 (40 μL) 200 μL
DNMBP-TPTE2-20-OROR 20 (40 μL) 200 μL
DNMBP-TPTE2-20-ORGO 20 (40 μL) 200 μL
DNMBP-TPTE2-20-ORAQ 20 (40 μL) 200 μL
DNMBP-TPTE2-20-GORE 20 (40 μL) 200 μL
DNMBP-TPTE2-20-GOOR 20 (40 μL) 200 μL
DNMBP-TPTE2-20-GOGO 20 (40 μL) 200 μL
DNMBP-TPTE2-20-GOGR 20 (40 μL) 200 μL
DNMBP-TPTE2-20-GOAQ 20 (40 μL) 200 μL
DNMBP-TPTE2-20-GRRE 20 (40 μL) 200 μL
DNMBP-TPTE2-20-GROR 20 (40 μL) 200 μL
DNMBP-TPTE2-20-GRGO 20 (40 μL) 200 μL
DNMBP-TPTE2-20-GRGR 20 (40 μL) 200 μL
DNMBP-TPTE2-20-GRAQ 20 (40 μL) 200 μL
DNMBP-TPTE2-20-AQRE 20 (40 μL) 200 μL
DNMBP-TPTE2-20-AQOR 20 (40 μL) 200 μL
DNMBP-TPTE2-20-AQGO 20 (40 μL) 200 μL
DNMBP-TPTE2-20-AQGR 20 (40 μL) 200 μL
DNMBP-TPTE2-20-AQAQ 20 (40 μL) 200 μL

DNMBP Gene Summary

This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Gene Name: Dynamin Binding Protein

Chromosome: CHR10: 101635333 -101769676

Locus: 10q24.2

TPTE2 Gene Summary

TPIP is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositol phospholipids.[supplied by OMIM, Jul 2002]

Gene Name: Transmembrane Phosphoinositide 3-phosphatase And Tensin Homolog 2

Chromosome: CHR13: 19997018 -20110903

Locus: 13q12.11

Gene Diseases

The DNMBP TPTE2 Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.