DST-TRIM38 Fusion FISH Probe
The DST-TRIM38 Fusion FISH Probe is used to confirm a fusion of the DST and TRIM38 genes. The fusion of the DST and TRIM38 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DST-TRIM38-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-RERE | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-REOR | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-REGO | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-REGR | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-REAQ | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-ORRE | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-OROR | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-ORGO | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-ORAQ | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-GORE | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-GOOR | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-GOGO | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-GOGR | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-GOAQ | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-GRRE | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-GROR | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-GRGO | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-GRGR | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-GRAQ | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-AQRE | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-AQOR | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-AQGO | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-AQGR | 20 (40 μL) | 200 μL |
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| DST-TRIM38-20-AQAQ | 20 (40 μL) | 200 μL |
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DST Gene Summary
This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been reported that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration. [provided by RefSeq, Mar 2010]
Gene Name: Dystonin
Chromosome: CHR6: 56322784 -56507694
Locus: 6p12.1
TRIM38 Gene Summary
This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012]
Gene Name: Tripartite Motif Containing 38
Chromosome: CHR6: 25963070 -25985352
Locus: 6p22.2
Gene Diseases
The DST TRIM38 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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