DTD1-TASP1 Fusion FISH Probe
The DTD1-TASP1 Fusion FISH Probe is used to confirm a fusion of the DTD1 and TASP1 genes. The fusion of the DTD1 and TASP1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DTD1-TASP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-RERE | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-REOR | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-REGO | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-REGR | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-REAQ | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-ORRE | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-OROR | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-ORGO | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-GORE | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-GOOR | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-GOGO | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-GOGR | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-GRRE | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-GROR | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-GRGO | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-GRGR | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-AQRE | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-AQOR | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-AQGO | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-AQGR | 20 (40 μL) | 200 μL |
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| DTD1-TASP1-20-AQAQ | 20 (40 μL) | 200 μL |
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TASP1 Gene Summary
This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Taspase 1
Chromosome: CHR20: 13370035 -13619583
Locus: 20p12.1
DTD1 Gene Summary
The protein encoded by this gene is similar in sequence to histidyl-tRNA synthetase, which hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). The encoded protein binds the DNA unwinding element and plays a role in the initiation of DNA replication. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Name: D-tyrosyl-tRNA Deacylase 1
Chromosome: CHR20: 18568555 -18744560
Locus: 20p11.23
Gene Diseases
The DTD1 TASP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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