DTNA-CD82 Fusion FISH Probe
The DTNA-CD82 Fusion FISH Probe is used to confirm a fusion of the DTNA and CD82 genes. The fusion of the DTNA and CD82 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DTNA-CD82-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-RERE | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-REOR | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-REGO | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-REGR | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-OROR | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-GORE | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-GROR | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| DTNA-CD82-20-AQAQ | 20 (40 μL) | 200 μL |
|
DTNA Gene Summary
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Dystrobrevin Alpha
Chromosome: CHR18: 32073253 -32471808
Locus: 18q12.1
CD82 Gene Summary
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: CD82 Molecule
Chromosome: CHR11: 44587140 -44641315
Locus: 11p11.2
Gene Diseases
The DTNA CD82 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|