DTNA-ZNF521 Fusion FISH Probe
The DTNA-ZNF521 Fusion FISH Probe is used to confirm a fusion of the DTNA and ZNF521 genes. The fusion of the DTNA and ZNF521 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DTNA-ZNF521-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-RERE | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-REOR | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-REGO | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-REGR | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-REAQ | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-ORRE | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-OROR | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-ORGO | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-ORAQ | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-GORE | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-GOOR | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-GOGO | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-GOGR | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-GOAQ | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-GRRE | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-GROR | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-GRGO | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-GRGR | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-GRAQ | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-AQRE | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-AQOR | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-AQGO | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-AQGR | 20 (40 μL) | 200 μL |
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| DTNA-ZNF521-20-AQAQ | 20 (40 μL) | 200 μL |
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DTNA Gene Summary
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Dystrobrevin Alpha
Chromosome: CHR18: 32073253 -32471808
Locus: 18q12.1
ZNF521 Gene Summary
The Zinc Finger Protein 521 (ZNF521) gene is located on chr18 :22641887-22932214 at 18q11.2.
Gene Name: Zinc Finger Protein 521
Chromosome: CHR18: 22641887 -22932214
Locus: 18q11.2
Gene Diseases
The DTNA ZNF521 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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