DUSP10-SUSD4 Fusion FISH Probe
The DUSP10-SUSD4 Fusion FISH Probe is used to confirm a fusion of the DUSP10 and SUSD4 genes. The fusion of the DUSP10 and SUSD4 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DUSP10-SUSD4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-RERE | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-REOR | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-REGO | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-REGR | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-REAQ | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-ORRE | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-OROR | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-ORGO | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-ORAQ | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-GORE | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-GOOR | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-GOGO | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-GOGR | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-GOAQ | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-GRRE | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-GROR | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-GRGO | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-GRGR | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-GRAQ | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-AQRE | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-AQOR | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-AQGO | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-AQGR | 20 (40 μL) | 200 μL |
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| DUSP10-SUSD4-20-AQAQ | 20 (40 μL) | 200 μL |
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DUSP10 Gene Summary
Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Name: Dual Specificity Phosphatase 10
Chromosome: CHR1: 221874763 -221915516
Locus: 1q41
SUSD4 Gene Summary
The Sushi Domain Containing 4 (SUSD4) gene is located on chr1 :223394160-223537544 at 1q41.
Gene Name: Sushi Domain Containing 4
Chromosome: CHR1: 223394160 -223537544
Locus: 1q41
Gene Diseases
The DUSP10 SUSD4 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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