DUSP12-CR2 Fusion FISH Probe
The DUSP12-CR2 Fusion FISH Probe is used to confirm a fusion of the DUSP12 and CR2 genes. The fusion of the DUSP12 and CR2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DUSP12-CR2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-RERE | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-REOR | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-REGO | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-REGR | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-REAQ | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-ORRE | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-OROR | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-ORGO | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-GORE | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-GOOR | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-GOGO | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-GOGR | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-GRRE | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-GROR | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-GRGO | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-GRGR | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-AQRE | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-AQOR | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-AQGO | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-AQGR | 20 (40 μL) | 200 μL |
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| DUSP12-CR2-20-AQAQ | 20 (40 μL) | 200 μL |
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CR2 Gene Summary
This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Name: Complement C3d Receptor 2
Chromosome: CHR1: 207627644 -207663240
Locus: 1q32.2
DUSP12 Gene Summary
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008]
Gene Name: Dual Specificity Phosphatase 12
Chromosome: CHR1: 161719580 -161726952
Locus: 1q23.3
Gene Diseases
The DUSP12 CR2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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