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DYNC1H1-EIF5 Fusion FISH Probe

The DYNC1H1-EIF5 Fusion FISH Probe is used to confirm a fusion of the DYNC1H1 and EIF5 genes. The fusion of the DYNC1H1 and EIF5 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DYNC1H1-EIF5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-RERE 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-REOR 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-REGO 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-REGR 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-REAQ 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-ORRE 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-OROR 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-ORGO 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-ORAQ 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-GORE 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-GOOR 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-GOGO 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-GOGR 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-GOAQ 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-GRRE 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-GROR 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-GRGO 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-GRGR 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-GRAQ 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-AQRE 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-AQOR 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-AQGO 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-AQGR 20 (40 μL) 200 μL
DYNC1H1-EIF5-20-AQAQ 20 (40 μL) 200 μL

DYNC1H1 Gene Summary

Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. [provided by RefSeq, Oct 2008]

Gene Name: Dynein Cytoplasmic 1 Heavy Chain 1

Chromosome: CHR14: 102430864 -102517135

Locus: 14q32.31

EIF5 Gene Summary

Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]

Gene Name: Eukaryotic Translation Initiation Factor 5

Chromosome: CHR14: 103800492 -103811361

Locus: 14q32.32

Gene Diseases

The DYNC1H1 EIF5 Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.