DYNC1I1-CXCL11 Fusion FISH Probe
The DYNC1I1-CXCL11 Fusion FISH Probe is used to confirm a fusion of the DYNC1I1 and CXCL11 genes. The fusion of the DYNC1I1 and CXCL11 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DYNC1I1-CXCL11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-RERE | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-REOR | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-REGO | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-REGR | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-REAQ | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-ORRE | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-OROR | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-ORGO | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-ORAQ | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-GORE | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-GOOR | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-GOGO | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-GOGR | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-GOAQ | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-GRRE | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-GROR | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-GRGO | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-GRGR | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-GRAQ | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-AQRE | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-AQOR | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-AQGO | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-AQGR | 20 (40 μL) | 200 μL |
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| DYNC1I1-CXCL11-20-AQAQ | 20 (40 μL) | 200 μL |
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DYNC1I1 Gene Summary
The Dynein Cytoplasmic 1 Intermediate Chain 1 (DYNC1I1) gene is located on chr7 :95401817-95727736 at 7q21.3.
Gene Name: Dynein Cytoplasmic 1 Intermediate Chain 1
Chromosome: CHR7: 95401817 -95727736
Locus: 7q21.3
CXCL11 Gene Summary
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Gene Name: C-X-C Motif Chemokine Ligand 11
Chromosome: CHR4: 76954839 -76957350
Locus: 4q21.1
Gene Diseases
The DYNC1I1 CXCL11 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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