DYNC2H1-KCNQ5 Fusion FISH Probe
The DYNC2H1-KCNQ5 Fusion FISH Probe is used to confirm a fusion of the DYNC2H1 and KCNQ5 genes. The fusion of the DYNC2H1 and KCNQ5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DYNC2H1-KCNQ5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-RERE | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-REOR | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-REGO | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-REGR | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-REAQ | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-ORRE | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-OROR | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-ORGO | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-ORAQ | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-GORE | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-GOOR | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-GOGO | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-GOGR | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-GOAQ | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-GRRE | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-GROR | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-GRGO | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-GRGR | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-GRAQ | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-AQRE | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-AQOR | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-AQGO | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-AQGR | 20 (40 μL) | 200 μL |
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| DYNC2H1-KCNQ5-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNQ5 Gene Summary
This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Name: Potassium Voltage-gated Channel Subfamily Q Member 5
Chromosome: CHR6: 73331570 -73908573
Locus: 6q13
DYNC2H1 Gene Summary
This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010]
Gene Name: Dynein Cytoplasmic 2 Heavy Chain 1
Chromosome: CHR11: 102980159 -103350591
Locus: 11q22.3
Gene Diseases
The DYNC2H1 KCNQ5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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