EAPP-SNX6 Fusion FISH Probe
The EAPP-SNX6 Fusion FISH Probe is used to confirm a fusion of the EAPP and SNX6 genes. The fusion of the EAPP and SNX6 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EAPP-SNX6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-RERE | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-REOR | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-REGO | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-REGR | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-REAQ | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-ORRE | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-OROR | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-ORGO | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-ORAQ | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-GORE | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-GOOR | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-GOGO | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-GOGR | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-GOAQ | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-GRRE | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-GROR | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-GRGO | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-GRGR | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-GRAQ | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-AQRE | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-AQOR | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-AQGO | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-AQGR | 20 (40 μL) | 200 μL |
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| EAPP-SNX6-20-AQAQ | 20 (40 μL) | 200 μL |
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EAPP Gene Summary
This gene encodes a phosphoprotein that interacts with several members of the E2F family of proteins. The protein localizes to the nucleus, and is present throughout the cell cycle except during mitosis. It functions to modulate E2F-regulated transcription and stimulate proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Name: E2F Associated Phosphoprotein
Chromosome: CHR14: 34985134 -35008943
Locus: 14q13.1
SNX6 Gene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Sorting Nexin 6
Chromosome: CHR14: 35030617 -35099366
Locus: 14q13.1
Gene Diseases
The EAPP SNX6 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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