ECE1-WNT4 Fusion FISH Probe
The ECE1-WNT4 Fusion FISH Probe is used to confirm a fusion of the ECE1 and WNT4 genes. The fusion of the ECE1 and WNT4 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ECE1-WNT4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-RERE | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-REOR | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-REGO | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-REGR | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-REAQ | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-ORRE | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-OROR | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-ORGO | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-ORAQ | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-GORE | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-GOOR | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-GOGO | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-GOGR | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-GOAQ | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-GRRE | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-GROR | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-GRGO | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-GRGR | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-GRAQ | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-AQRE | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-AQOR | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-AQGO | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-AQGR | 20 (40 μL) | 200 μL |
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| ECE1-WNT4-20-AQAQ | 20 (40 μL) | 200 μL |
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ECE1 Gene Summary
The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Sep 2009]
Gene Name: Endothelin Converting Enzyme 1
Chromosome: CHR1: 21543739 -21672034
Locus: 1p36.12
WNT4 Gene Summary
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq, Jul 2008]
Gene Name: Wnt Family Member 4
Chromosome: CHR1: 22443797 -22469519
Locus: 1p36.12
Gene Diseases
The ECE1 WNT4 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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