EFHC1-IL17A Fusion FISH Probe
The EFHC1-IL17A Fusion FISH Probe is used to confirm a fusion of the EFHC1 and IL17A genes. The fusion of the EFHC1 and IL17A genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EFHC1-IL17A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-RERE | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-REOR | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-REGO | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-REGR | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-REAQ | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-ORRE | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-OROR | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-ORGO | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-ORAQ | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-GORE | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-GOOR | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-GOGO | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-GOGR | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-GOAQ | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-GRRE | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-GROR | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-GRGO | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-GRGR | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-GRAQ | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-AQRE | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-AQOR | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-AQGO | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-AQGR | 20 (40 μL) | 200 μL |
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| EFHC1-IL17A-20-AQAQ | 20 (40 μL) | 200 μL |
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IL17A Gene Summary
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
Gene Name: Interleukin 17A
Chromosome: CHR6: 52051184 -52055436
Locus: 6p12.2
EFHC1 Gene Summary
This gene encodes an EF-hand-containing calcium binding protein. The encoded protein likely plays a role in calcium homeostasis. Mutations in this gene have been associated with susceptibility to juvenile myoclonic epilepsy and juvenile absence epilepsy. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]
Gene Name: EF-hand Domain Containing 1
Chromosome: CHR6: 52284993 -52360583
Locus: 6p12.2
Gene Diseases
The EFHC1 IL17A Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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