EFR3A-ZFAT Fusion FISH Probe
The EFR3A-ZFAT Fusion FISH Probe is used to confirm a fusion of the EFR3A and ZFAT genes. The fusion of the EFR3A and ZFAT genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EFR3A-ZFAT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-RERE | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-REOR | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-REGO | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-REGR | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-REAQ | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-ORRE | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-OROR | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-ORGO | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-ORAQ | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-GORE | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-GOOR | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-GOGO | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-GOGR | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-GOAQ | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-GRRE | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-GROR | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-GRGO | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-GRGR | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-GRAQ | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-AQRE | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-AQOR | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-AQGO | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-AQGR | 20 (40 μL) | 200 μL |
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| EFR3A-ZFAT-20-AQAQ | 20 (40 μL) | 200 μL |
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EFR3A Gene Summary
The protein encoded by this gene is part of a complex that plays a role in maintaining an active pool of phosphatidylinositol 4-kinase (PI4K) at the plasma membrane. This protein is thought to be a peripheral membrane protein that associates with the plasma membrane through palmitoylation. Studies indicate that this gene product plays a role in controlling G protein-coupled receptor (GPCR) activity by affecting receptor phosphorylation. Whole exome sequencing studies have implicated mutations in this gene with autism spectrum disorders. [provided by RefSeq, Apr 2016]
Gene Name: EFR3 Homolog A
Chromosome: CHR8: 132916355 -133025886
Locus: 8q24.22
ZFAT Gene Summary
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]
Gene Name: Zinc Finger And AT-hook Domain Containing
Chromosome: CHR8: 135490030 -135725292
Locus: 8q24.22
Gene Diseases
The EFR3A ZFAT Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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