ELOVL5-SLC25A27 Fusion FISH Probe
The ELOVL5-SLC25A27 Fusion FISH Probe is used to confirm a fusion of the ELOVL5 and SLC25A27 genes. The fusion of the ELOVL5 and SLC25A27 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ELOVL5-SLC25A27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-RERE | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-REOR | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-REGO | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-REGR | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-REAQ | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-ORRE | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-OROR | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-ORGO | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-ORAQ | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-GORE | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-GOOR | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-GOGO | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-GOGR | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-GOAQ | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-GRRE | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-GROR | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-GRGO | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-GRGR | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-GRAQ | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-AQRE | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-AQOR | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-AQGO | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-AQGR | 20 (40 μL) | 200 μL |
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| ELOVL5-SLC25A27-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC25A27 Gene Summary
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
Gene Name: Solute Carrier Family 25 Member 27
Chromosome: CHR6: 46620651 -46645927
Locus: 6p12.3
ELOVL5 Gene Summary
This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
Gene Name: ELOVL Fatty Acid Elongase 5
Chromosome: CHR6: 53132195 -53213977
Locus: 6p12.1
Gene Diseases
The ELOVL5 SLC25A27 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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