EML4-PKDCC Fusion FISH Probe
The EML4-PKDCC Fusion FISH Probe is used to confirm a fusion of the EML4 and PKDCC genes. The fusion of the EML4 and PKDCC genes has been associated with Uterine Corpus Endometrial Carcinoma, and Pheochromocytoma And Paraganglioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EML4-PKDCC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-RERE | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-REOR | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-REGO | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-REGR | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-OROR | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-GORE | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-GROR | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| EML4-PKDCC-20-AQAQ | 20 (40 μL) | 200 μL |
|
EML4 Gene Summary
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]
Gene Name: Echinoderm Microtubule Associated Protein Like 4
Chromosome: CHR2: 42396489 -42559688
Locus: 2p21
PKDCC Gene Summary
The Protein Kinase Domain Containing, Cytoplasmic (PKDCC) gene is located on chr2 :42275160-42285668 at 2p21.
Gene Name: Protein Kinase Domain Containing, Cytoplasmic
Chromosome: CHR2: 42275160 -42285668
Locus: 2p21
Gene Diseases
The EML4 PKDCC Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Corpus Endometrial Carcinoma |
| Pheochromocytoma And Paraganglioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|