ENO1-SIAE Fusion FISH Probe
The ENO1-SIAE Fusion FISH Probe is used to confirm a fusion of the ENO1 and SIAE genes. The fusion of the ENO1 and SIAE genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ENO1-SIAE-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-RERE | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-REOR | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-REGO | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-REGR | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-REAQ | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-ORRE | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-OROR | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-ORGO | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-ORAQ | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-GORE | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-GOOR | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-GOGO | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-GOGR | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-GOAQ | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-GRRE | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-GROR | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-GRGO | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-GRGR | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-GRAQ | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-AQRE | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-AQOR | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-AQGO | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-AQGR | 20 (40 μL) | 200 μL |
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| ENO1-SIAE-20-AQAQ | 20 (40 μL) | 200 μL |
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ENO1 Gene Summary
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]
Gene Name: Enolase 1
Chromosome: CHR1: 8921058 -8939151
Locus: 1p36.23
SIAE Gene Summary
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Name: Sialic Acid Acetylesterase
Chromosome: CHR11: 124505684 -124546199
Locus: 11q24.2
Gene Diseases
The ENO1 SIAE Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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