ENO1-UVRAG Fusion FISH Probe
The ENO1-UVRAG Fusion FISH Probe is used to confirm a fusion of the ENO1 and UVRAG genes. The fusion of the ENO1 and UVRAG genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ENO1-UVRAG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-RERE | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-REOR | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-REGO | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-REGR | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-REAQ | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-ORRE | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-OROR | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-ORGO | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-ORAQ | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-GORE | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-GOOR | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-GOGO | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-GOGR | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-GOAQ | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-GRRE | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-GROR | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-GRGO | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-GRGR | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-GRAQ | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-AQRE | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-AQOR | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-AQGO | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-AQGR | 20 (40 μL) | 200 μL |
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| ENO1-UVRAG-20-AQAQ | 20 (40 μL) | 200 μL |
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ENO1 Gene Summary
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]
Gene Name: Enolase 1
Chromosome: CHR1: 8921058 -8939151
Locus: 1p36.23
UVRAG Gene Summary
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008]
Gene Name: UV Radiation Resistance Associated
Chromosome: CHR11: 75526211 -75855282
Locus: 11q13.5
Gene Diseases
The ENO1 UVRAG Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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