ENPP1-CDX1 Fusion FISH Probe
The ENPP1-CDX1 Fusion FISH Probe is used to confirm a fusion of the ENPP1 and CDX1 genes. The fusion of the ENPP1 and CDX1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ENPP1-CDX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-RERE | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-REOR | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-REGO | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-REGR | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-REAQ | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-ORRE | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-OROR | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-ORGO | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-GORE | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-GOOR | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-GOGO | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-GOGR | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-GRRE | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-GROR | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-GRGO | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-GRGR | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-AQRE | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-AQOR | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-AQGO | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-AQGR | 20 (40 μL) | 200 μL |
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| ENPP1-CDX1-20-AQAQ | 20 (40 μL) | 200 μL |
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CDX1 Gene Summary
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity. [provided by RefSeq, Jul 2008]
Gene Name: Caudal Type Homeobox 1
Chromosome: CHR5: 149546343 -149564121
Locus: 5q32
ENPP1 Gene Summary
This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008]
Gene Name: Ectonucleotide Pyrophosphatase/phosphodiesterase 1
Chromosome: CHR6: 132129155 -132216295
Locus: 6q23.2
Gene Diseases
The ENPP1 CDX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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