EPHA2-FBXO42 Fusion FISH Probe
The EPHA2-FBXO42 Fusion FISH Probe is used to confirm a fusion of the EPHA2 and FBXO42 genes. The fusion of the EPHA2 and FBXO42 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EPHA2-FBXO42-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-RERE | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-REOR | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-REGO | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-REGR | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-REAQ | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-ORRE | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-OROR | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-ORGO | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-ORAQ | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-GORE | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-GOOR | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-GOGO | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-GOGR | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-GOAQ | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-GRRE | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-GROR | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-GRGO | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-GRGR | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-GRAQ | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-AQRE | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-AQOR | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-AQGO | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-AQGR | 20 (40 μL) | 200 μL |
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| EPHA2-FBXO42-20-AQAQ | 20 (40 μL) | 200 μL |
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EPHA2 Gene Summary
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]
Gene Name: EPH Receptor A2
Chromosome: CHR1: 16450831 -16482582
Locus: 1p36.13
FBXO42 Gene Summary
Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Dec 2010]
Gene Name: F-box Protein 42
Chromosome: CHR1: 16576558 -16678948
Locus: 1p36.13
Gene Diseases
The EPHA2 FBXO42 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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