EPRS-USH2A Fusion FISH Probe
The EPRS-USH2A Fusion FISH Probe is used to confirm a fusion of the EPRS and USH2A genes. The fusion of the EPRS and USH2A genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EPRS-USH2A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-RERE | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-REOR | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-REGO | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-REGR | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-REAQ | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-ORRE | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-OROR | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-ORGO | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-ORAQ | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-GORE | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-GOOR | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-GOGO | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-GOGR | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-GOAQ | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-GRRE | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-GROR | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-GRGO | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-GRGR | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-GRAQ | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-AQRE | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-AQOR | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-AQGO | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-AQGR | 20 (40 μL) | 200 μL |
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| EPRS-USH2A-20-AQAQ | 20 (40 μL) | 200 μL |
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EPRS Gene Summary
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Glutamyl-prolyl-tRNA Synthetase
Chromosome: CHR1: 220141941 -220220000
Locus: 1q41
USH2A Gene Summary
This gene encodes a protein that contains laminin EGF motifs, a pentaxin domain, and many fibronectin type III motifs. The protein is found in the basement membrane, and may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIa and retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: Usherin
Chromosome: CHR1: 215796235 -216596738
Locus: 1q41
Gene Diseases
The EPRS USH2A Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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