EPS15-OSBPL9 Fusion FISH Probe
The EPS15-OSBPL9 Fusion FISH Probe is used to confirm a fusion of the EPS15 and OSBPL9 genes. The fusion of the EPS15 and OSBPL9 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EPS15-OSBPL9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-RERE | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-REOR | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-REGO | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-REGR | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-REAQ | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-ORRE | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-OROR | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-ORGO | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-ORAQ | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-GORE | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-GOOR | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-GOGO | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-GOGR | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-GOAQ | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-GRRE | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-GROR | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-GRGO | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-GRGR | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-GRAQ | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-AQRE | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-AQOR | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-AQGO | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-AQGR | 20 (40 μL) | 200 μL |
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| EPS15-OSBPL9-20-AQAQ | 20 (40 μL) | 200 μL |
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EPS15 Gene Summary
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009]
Gene Name: Epidermal Growth Factor Receptor Pathway Substrate 15
Chromosome: CHR1: 51819934 -51984995
Locus: 1p32.3
OSBPL9 Gene Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12. [provided by RefSeq, Jul 2010]
Gene Name: Oxysterol Binding Protein Like 9
Chromosome: CHR1: 52082545 -52254891
Locus: 1p32.3
Gene Diseases
The EPS15 OSBPL9 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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