ERC1-PIK3C2G Fusion FISH Probe
The ERC1-PIK3C2G Fusion FISH Probe is used to confirm a fusion of the ERC1 and PIK3C2G genes. The fusion of the ERC1 and PIK3C2G genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ERC1-PIK3C2G-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-RERE | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-REOR | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-REGO | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-REGR | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-REAQ | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-ORRE | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-OROR | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-ORGO | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-ORAQ | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-GORE | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-GOOR | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-GOGO | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-GOGR | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-GOAQ | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-GRRE | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-GROR | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-GRGO | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-GRGR | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-GRAQ | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-AQRE | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-AQOR | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-AQGO | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-AQGR | 20 (40 μL) | 200 μL |
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| ERC1-PIK3C2G-20-AQAQ | 20 (40 μL) | 200 μL |
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PIK3C2G Gene Summary
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Name: Phosphatidylinositol-4-phosphate 3-kinase Catalytic Subunit Type 2 Gamma
Chromosome: CHR12: 18414473 -18801352
Locus: 12p12.3
ERC1 Gene Summary
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: ELKS/RAB6-interacting/CAST Family Member 1
Chromosome: CHR12: 1100403 -1605099
Locus: 12p13.33
Gene Diseases
The ERC1 PIK3C2G Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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