ERCC2-MYH14 Fusion FISH Probe
The ERCC2-MYH14 Fusion FISH Probe is used to confirm a fusion of the ERCC2 and MYH14 genes. The fusion of the ERCC2 and MYH14 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ERCC2-MYH14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-RERE | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-REOR | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-REGO | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-REGR | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-REAQ | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-ORRE | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-OROR | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-ORGO | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-ORAQ | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-GORE | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-GOOR | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-GOGO | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-GOGR | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-GOAQ | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-GRRE | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-GROR | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-GRGO | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-GRGR | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-GRAQ | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-AQRE | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-AQOR | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-AQGO | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-AQGR | 20 (40 μL) | 200 μL |
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| ERCC2-MYH14-20-AQAQ | 20 (40 μL) | 200 μL |
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ERCC2 Gene Summary
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Name: ERCC Excision Repair 2, TFIIH Core Complex Helicase Subunit
Chromosome: CHR19: 45854648 -45873845
Locus: 19q13.32
MYH14 Gene Summary
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Heavy Chain 14
Chromosome: CHR19: 50706884 -50813801
Locus: 19q13.33
Gene Diseases
The ERCC2 MYH14 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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