ERLIN1-HPSE2 Fusion FISH Probe
The ERLIN1-HPSE2 Fusion FISH Probe is used to confirm a fusion of the ERLIN1 and HPSE2 genes. The fusion of the ERLIN1 and HPSE2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ERLIN1-HPSE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-RERE | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-REOR | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-REGO | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-REGR | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-REAQ | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-ORRE | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-OROR | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-ORGO | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-GORE | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-GOOR | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-GOGO | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-GOGR | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-GRRE | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-GROR | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-GRGO | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-GRGR | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-AQRE | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-AQOR | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-AQGO | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-AQGR | 20 (40 μL) | 200 μL |
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| ERLIN1-HPSE2-20-AQAQ | 20 (40 μL) | 200 μL |
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ERLIN1 Gene Summary
The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62. [provided by RefSeq, Dec 2016]
Gene Name: ER Lipid Raft Associated 1
Chromosome: CHR10: 101909846 -101945814
Locus: 10q24.31
HPSE2 Gene Summary
This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: Heparanase 2 (inactive)
Chromosome: CHR10: 100216833 -100995632
Locus: 10q24.2
Gene Diseases
The ERLIN1 HPSE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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