ERMP1-RBBP8 Fusion FISH Probe
The ERMP1-RBBP8 Fusion FISH Probe is used to confirm a fusion of the ERMP1 and RBBP8 genes. The fusion of the ERMP1 and RBBP8 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ERMP1-RBBP8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-RERE | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-REOR | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-REGO | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-REGR | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-REAQ | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-ORRE | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-OROR | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-ORGO | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-ORAQ | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-GORE | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-GOOR | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-GOGO | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-GOGR | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-GOAQ | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-GRRE | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-GROR | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-GRGO | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-GRGR | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-GRAQ | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-AQRE | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-AQOR | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-AQGO | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-AQGR | 20 (40 μL) | 200 μL |
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| ERMP1-RBBP8-20-AQAQ | 20 (40 μL) | 200 μL |
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RBBP8 Gene Summary
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]
Gene Name: RB Binding Protein 8, Endonuclease
Chromosome: CHR18: 20513294 -20606449
Locus: 18q11.2
ERMP1 Gene Summary
The Endoplasmic Reticulum Metallopeptidase 1 (ERMP1) gene is located on chr9 :5784571-5833081 at 9p24.1.
Gene Name: Endoplasmic Reticulum Metallopeptidase 1
Chromosome: CHR9: 5784571 -5833081
Locus: 9p24.1
Gene Diseases
The ERMP1 RBBP8 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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