ERRFI1-CACNA1E Fusion FISH Probe
The ERRFI1-CACNA1E Fusion FISH Probe is used to confirm a fusion of the ERRFI1 and CACNA1E genes. The fusion of the ERRFI1 and CACNA1E genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ERRFI1-CACNA1E-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-RERE | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-REOR | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-REGO | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-REGR | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-REAQ | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-ORRE | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-OROR | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-ORGO | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-ORAQ | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-GORE | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-GOOR | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-GOGO | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-GOGR | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-GOAQ | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-GRRE | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-GROR | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-GRGO | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-GRGR | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-GRAQ | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-AQRE | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-AQOR | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-AQGO | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-AQGR | 20 (40 μL) | 200 μL |
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| ERRFI1-CACNA1E-20-AQAQ | 20 (40 μL) | 200 μL |
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CACNA1E Gene Summary
Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
Gene Name: Calcium Voltage-gated Channel Subunit Alpha1 E
Chromosome: CHR1: 181452685 -181775921
Locus: 1q25.3
ERRFI1 Gene Summary
ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885]; Fiorentino et al., 2000 [PubMed 11003669]).[supplied by OMIM, Mar 2008]
Gene Name: ERBB Receptor Feedback Inhibitor 1
Chromosome: CHR1: 8071778 -8086393
Locus: 1p36.23
Gene Diseases
The ERRFI1 CACNA1E Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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