ESR1-BNC2 Fusion FISH Probe
The ESR1-BNC2 Fusion FISH Probe is used to confirm a fusion of the ESR1 and BNC2 genes. The fusion of the ESR1 and BNC2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ESR1-BNC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-RERE | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-REOR | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-REGO | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-REGR | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-REAQ | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-ORRE | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-OROR | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-ORGO | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-GORE | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-GOOR | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-GOGO | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-GOGR | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-GRRE | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-GROR | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-GRGO | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-GRGR | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-AQRE | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-AQOR | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-AQGO | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-AQGR | 20 (40 μL) | 200 μL |
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| ESR1-BNC2-20-AQAQ | 20 (40 μL) | 200 μL |
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ESR1 Gene Summary
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
Gene Name: Estrogen Receptor 1
Chromosome: CHR6: 152011630 -152424408
Locus: 6q25.1-q25.2
BNC2 Gene Summary
This gene encodes a conserved zinc finger protein. The encoded protein functions in skin color saturation. Mutations in this gene are associated with facial pigmented spots. This gene is also associated with susceptibility to adolescent idiopathic scoliosis. [provided by RefSeq, Jul 2016]
Gene Name: Basonuclin 2
Chromosome: CHR9: 16409500 -16870786
Locus: 9p22.3-p22.2
Gene Diseases
The ESR1 BNC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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