ETFA-STRA6 Fusion FISH Probe
The ETFA-STRA6 Fusion FISH Probe is used to confirm a fusion of the ETFA and STRA6 genes. The fusion of the ETFA and STRA6 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ETFA-STRA6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-RERE | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-REOR | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-REGO | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-REGR | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-REAQ | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-ORRE | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-OROR | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-ORGO | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-ORAQ | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-GORE | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-GOOR | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-GOGO | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-GOGR | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-GOAQ | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-GRRE | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-GROR | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-GRGO | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-GRGR | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-GRAQ | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-AQRE | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-AQOR | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-AQGO | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-AQGR | 20 (40 μL) | 200 μL |
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| ETFA-STRA6-20-AQAQ | 20 (40 μL) | 200 μL |
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ETFA Gene Summary
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Electron Transfer Flavoprotein Alpha Subunit
Chromosome: CHR15: 76508628 -76603810
Locus: 15q24.2-q24.3
STRA6 Gene Summary
The protein encoded by this gene is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9). Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: Stimulated By Retinoic Acid 6
Chromosome: CHR15: 74471807 -74502046
Locus: 15q24.1
Gene Diseases
The ETFA STRA6 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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