ETNK2-REN Fusion FISH Probe
The ETNK2-REN Fusion FISH Probe is used to confirm a fusion of the ETNK2 and REN genes. The fusion of the ETNK2 and REN genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ETNK2-REN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ETNK2-REN-20-AQAQ | 20 (40 μL) | 200 μL |
|
REN Gene Summary
Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]
Gene Name: Renin
Chromosome: CHR1: 204123943 -204135465
Locus: 1q32.1
ETNK2 Gene Summary
The protein encoded by this gene is a member of choline/ethanolamine kinase family which catalyzes the first step of phosphatidylethanolamine (PtdEtn) biosynthesis via the cytidine diphosphate (CDP) ethanolamine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: Ethanolamine Kinase 2
Chromosome: CHR1: 204100189 -204121307
Locus: 1q32.1
Gene Diseases
The ETNK2 REN Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|