ETV6-DUSP16 Fusion FISH Probe
The ETV6-DUSP16 Fusion FISH Probe is used to confirm a fusion of the ETV6 and DUSP16 genes. The fusion of the ETV6 and DUSP16 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ETV6-DUSP16-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-RERE | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-REOR | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-REGO | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-REGR | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-REAQ | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-ORRE | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-OROR | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-ORGO | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-ORAQ | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-GORE | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-GOOR | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-GOGO | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-GOGR | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-GOAQ | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-GRRE | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-GROR | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-GRGO | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-GRGR | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-GRAQ | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-AQRE | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-AQOR | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-AQGO | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-AQGR | 20 (40 μL) | 200 μL |
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| ETV6-DUSP16-20-AQAQ | 20 (40 μL) | 200 μL |
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ETV6 Gene Summary
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008]
Gene Name: ETS Variant 6
Chromosome: CHR12: 11802787 -12048325
Locus: 12p13.2
DUSP16 Gene Summary
This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010]
Gene Name: Dual Specificity Phosphatase 16
Chromosome: CHR12: 12626215 -12715448
Locus: 12p13.2
Gene Diseases
The ETV6 DUSP16 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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