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EXOC2-RNF144B Fusion FISH Probe

The EXOC2-RNF144B Fusion FISH Probe is used to confirm a fusion of the EXOC2 and RNF144B genes. The fusion of the EXOC2 and RNF144B genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
EXOC2-RNF144B-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
EXOC2-RNF144B-20-RERE 20 (40 μL) 200 μL
EXOC2-RNF144B-20-REOR 20 (40 μL) 200 μL
EXOC2-RNF144B-20-REGO 20 (40 μL) 200 μL
EXOC2-RNF144B-20-REGR 20 (40 μL) 200 μL
EXOC2-RNF144B-20-REAQ 20 (40 μL) 200 μL
EXOC2-RNF144B-20-ORRE 20 (40 μL) 200 μL
EXOC2-RNF144B-20-OROR 20 (40 μL) 200 μL
EXOC2-RNF144B-20-ORGO 20 (40 μL) 200 μL
EXOC2-RNF144B-20-ORAQ 20 (40 μL) 200 μL
EXOC2-RNF144B-20-GORE 20 (40 μL) 200 μL
EXOC2-RNF144B-20-GOOR 20 (40 μL) 200 μL
EXOC2-RNF144B-20-GOGO 20 (40 μL) 200 μL
EXOC2-RNF144B-20-GOGR 20 (40 μL) 200 μL
EXOC2-RNF144B-20-GOAQ 20 (40 μL) 200 μL
EXOC2-RNF144B-20-GRRE 20 (40 μL) 200 μL
EXOC2-RNF144B-20-GROR 20 (40 μL) 200 μL
EXOC2-RNF144B-20-GRGO 20 (40 μL) 200 μL
EXOC2-RNF144B-20-GRGR 20 (40 μL) 200 μL
EXOC2-RNF144B-20-GRAQ 20 (40 μL) 200 μL
EXOC2-RNF144B-20-AQRE 20 (40 μL) 200 μL
EXOC2-RNF144B-20-AQOR 20 (40 μL) 200 μL
EXOC2-RNF144B-20-AQGO 20 (40 μL) 200 μL
EXOC2-RNF144B-20-AQGR 20 (40 μL) 200 μL
EXOC2-RNF144B-20-AQAQ 20 (40 μL) 200 μL

EXOC2 Gene Summary

The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Gene Name: Exocyst Complex Component 2

Chromosome: CHR6: 485137 -693109

Locus: 6p25.3

RNF144B Gene Summary

The Ring Finger Protein 144B (RNF144B) gene is located on chr6 :18387580-18469105 at 6p22.3.

Gene Name: Ring Finger Protein 144B

Chromosome: CHR6: 18387580 -18469105

Locus: 6p22.3

Gene Diseases

The EXOC2 RNF144B Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.