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FAM73B-P4HB Fusion FISH Probe

The FAM73B-P4HB Fusion FISH Probe is used to confirm a fusion of the FAM73B and P4HB genes. The fusion of the FAM73B and P4HB genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FAM73B-P4HB-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
FAM73B-P4HB-20-RERE 20 (40 μL) 200 μL
FAM73B-P4HB-20-REOR 20 (40 μL) 200 μL
FAM73B-P4HB-20-REGO 20 (40 μL) 200 μL
FAM73B-P4HB-20-REGR 20 (40 μL) 200 μL
FAM73B-P4HB-20-REAQ 20 (40 μL) 200 μL
FAM73B-P4HB-20-ORRE 20 (40 μL) 200 μL
FAM73B-P4HB-20-OROR 20 (40 μL) 200 μL
FAM73B-P4HB-20-ORGO 20 (40 μL) 200 μL
FAM73B-P4HB-20-ORAQ 20 (40 μL) 200 μL
FAM73B-P4HB-20-GORE 20 (40 μL) 200 μL
FAM73B-P4HB-20-GOOR 20 (40 μL) 200 μL
FAM73B-P4HB-20-GOGO 20 (40 μL) 200 μL
FAM73B-P4HB-20-GOGR 20 (40 μL) 200 μL
FAM73B-P4HB-20-GOAQ 20 (40 μL) 200 μL
FAM73B-P4HB-20-GRRE 20 (40 μL) 200 μL
FAM73B-P4HB-20-GROR 20 (40 μL) 200 μL
FAM73B-P4HB-20-GRGO 20 (40 μL) 200 μL
FAM73B-P4HB-20-GRGR 20 (40 μL) 200 μL
FAM73B-P4HB-20-GRAQ 20 (40 μL) 200 μL
FAM73B-P4HB-20-AQRE 20 (40 μL) 200 μL
FAM73B-P4HB-20-AQOR 20 (40 μL) 200 μL
FAM73B-P4HB-20-AQGO 20 (40 μL) 200 μL
FAM73B-P4HB-20-AQGR 20 (40 μL) 200 μL
FAM73B-P4HB-20-AQAQ 20 (40 μL) 200 μL

P4HB Gene Summary

This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]

Gene Name: Prolyl 4-hydroxylase Subunit Beta

Chromosome: CHR17: 79801033 -79818544

Locus: 17q25.3

Gene Diseases

The FAM73B P4HB Fusion has been associated with the following diseases:

Disease Name
Uterine Carcinosarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.