FAM83G-GRAP Fusion FISH Probe
The FAM83G-GRAP Fusion FISH Probe is used to confirm a fusion of the FAM83G and GRAP genes. The fusion of the FAM83G and GRAP genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM83G-GRAP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-RERE | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-REOR | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-REGO | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-REGR | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-OROR | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-GORE | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-GROR | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM83G-GRAP-20-AQAQ | 20 (40 μL) | 200 μL |
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GRAP Gene Summary
This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012]
Gene Name: GRB2-related Adaptor Protein
Chromosome: CHR17: 18923989 -18950336
Locus: 17p11.2
FAM83G Gene Summary
The Family With Sequence Similarity 83 Member G (FAM83G) gene is located on chr17 :18874380-18908060 at 17p11.2.
Gene Name: Family With Sequence Similarity 83 Member G
Chromosome: CHR17: 18874380 -18908060
Locus: 17p11.2
Gene Diseases
The FAM83G GRAP Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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