FANCA-SPIRE2 Fusion FISH Probe
The FANCA-SPIRE2 Fusion FISH Probe is used to confirm a fusion of the FANCA and SPIRE2 genes. The fusion of the FANCA and SPIRE2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FANCA-SPIRE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-RERE | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-REOR | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-REGO | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-REGR | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-REAQ | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-ORRE | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-OROR | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-ORGO | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-GORE | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-GOOR | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-GOGO | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-GOGR | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-GRRE | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-GROR | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-GRGO | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-GRGR | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-AQRE | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-AQOR | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-AQGO | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-AQGR | 20 (40 μL) | 200 μL |
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| FANCA-SPIRE2-20-AQAQ | 20 (40 μL) | 200 μL |
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FANCA Gene Summary
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq, Jul 2008]
Gene Name: Fanconi Anemia Complementation Group A
Chromosome: CHR16: 89803958 -89883065
Locus: 16q24.3
SPIRE2 Gene Summary
The Spire Type Actin Nucleation Factor 2 (SPIRE2) gene is located on chr16 :89894906-89937727 at 16q24.3.
Gene Name: Spire Type Actin Nucleation Factor 2
Chromosome: CHR16: 89894906 -89937727
Locus: 16q24.3
Gene Diseases
The FANCA SPIRE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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