FANCI-ABHD2 Fusion FISH Probe
The FANCI-ABHD2 Fusion FISH Probe is used to confirm a fusion of the FANCI and ABHD2 genes. The fusion of the FANCI and ABHD2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FANCI-ABHD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-RERE | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-REOR | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-REGO | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-REGR | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-REAQ | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-ORRE | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-OROR | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-ORGO | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-GORE | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-GOOR | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-GOGO | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-GOGR | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-GRRE | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-GROR | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-GRGO | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-GRGR | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-AQRE | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-AQOR | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-AQGO | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-AQGR | 20 (40 μL) | 200 μL |
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| FANCI-ABHD2-20-AQAQ | 20 (40 μL) | 200 μL |
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ABHD2 Gene Summary
This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a wide range of enzymes. The encoded protein is an acylglycerol lipase that catalyzes the hydrolysis of endocannabinoid arachidonoylglycerol from the cell membrane. This leads to activation of the sperm calcium channel CatSper, which results in sperm activation. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jan 2017]
Gene Name: Abhydrolase Domain Containing 2
Chromosome: CHR15: 89631380 -89745591
Locus: 15q26.1
FANCI Gene Summary
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Fanconi Anemia Complementation Group I
Chromosome: CHR15: 89787193 -89860362
Locus: 15q26.1
Gene Diseases
The FANCI ABHD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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