FANCM-PRPF39 Fusion FISH Probe
The FANCM-PRPF39 Fusion FISH Probe is used to confirm a fusion of the FANCM and PRPF39 genes. The fusion of the FANCM and PRPF39 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FANCM-PRPF39-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-RERE | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-REOR | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-REGO | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-REGR | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-REAQ | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-ORRE | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-OROR | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-ORGO | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-ORAQ | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-GORE | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-GOOR | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-GOGO | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-GOGR | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-GOAQ | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-GRRE | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-GROR | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-GRGO | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-GRGR | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-GRAQ | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-AQRE | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-AQOR | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-AQGO | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-AQGR | 20 (40 μL) | 200 μL |
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| FANCM-PRPF39-20-AQAQ | 20 (40 μL) | 200 μL |
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PRPF39 Gene Summary
The Pre-mRNA Processing Factor 39 (PRPF39) gene is located on chr14 :45553301-45584804 at 14q21.2.
Gene Name: Pre-mRNA Processing Factor 39
Chromosome: CHR14: 45553301 -45584804
Locus: 14q21.2
FANCM Gene Summary
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Name: Fanconi Anemia Complementation Group M
Chromosome: CHR14: 45605135 -45670093
Locus: 14q21.2
Gene Diseases
The FANCM PRPF39 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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