FASN-CCDC57 Fusion FISH Probe
The FASN-CCDC57 Fusion FISH Probe is used to confirm a fusion of the FASN and CCDC57 genes. The fusion of the FASN and CCDC57 genes has been associated with Ovarian Serous Cystadenocarcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FASN-CCDC57-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-RERE | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-REOR | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-REGO | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-REGR | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-REAQ | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-ORRE | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-OROR | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-ORGO | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-ORAQ | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-GORE | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-GOOR | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-GOGO | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-GOGR | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-GOAQ | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-GRRE | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-GROR | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-GRGO | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-GRGR | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-GRAQ | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-AQRE | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-AQOR | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-AQGO | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-AQGR | 20 (40 μL) | 200 μL |
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| FASN-CCDC57-20-AQAQ | 20 (40 μL) | 200 μL |
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FASN Gene Summary
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
Gene Name: Fatty Acid Synthase
Chromosome: CHR17: 80036213 -80056106
Locus: 17q25.3
CCDC57 Gene Summary
The Coiled-coil Domain Containing 57 (CCDC57) gene is located on chr17 :80059345-80170689 at 17q25.3.
Gene Name: Coiled-coil Domain Containing 57
Chromosome: CHR17: 80059345 -80170689
Locus: 17q25.3
Gene Diseases
The FASN CCDC57 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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