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FBN1-EIF3B Fusion FISH Probe

The FBN1-EIF3B Fusion FISH Probe is used to confirm a fusion of the FBN1 and EIF3B genes. The fusion of the FBN1 and EIF3B genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FBN1-EIF3B-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
FBN1-EIF3B-20-RERE 20 (40 μL) 200 μL
FBN1-EIF3B-20-REOR 20 (40 μL) 200 μL
FBN1-EIF3B-20-REGO 20 (40 μL) 200 μL
FBN1-EIF3B-20-REGR 20 (40 μL) 200 μL
FBN1-EIF3B-20-REAQ 20 (40 μL) 200 μL
FBN1-EIF3B-20-ORRE 20 (40 μL) 200 μL
FBN1-EIF3B-20-OROR 20 (40 μL) 200 μL
FBN1-EIF3B-20-ORGO 20 (40 μL) 200 μL
FBN1-EIF3B-20-ORAQ 20 (40 μL) 200 μL
FBN1-EIF3B-20-GORE 20 (40 μL) 200 μL
FBN1-EIF3B-20-GOOR 20 (40 μL) 200 μL
FBN1-EIF3B-20-GOGO 20 (40 μL) 200 μL
FBN1-EIF3B-20-GOGR 20 (40 μL) 200 μL
FBN1-EIF3B-20-GOAQ 20 (40 μL) 200 μL
FBN1-EIF3B-20-GRRE 20 (40 μL) 200 μL
FBN1-EIF3B-20-GROR 20 (40 μL) 200 μL
FBN1-EIF3B-20-GRGO 20 (40 μL) 200 μL
FBN1-EIF3B-20-GRGR 20 (40 μL) 200 μL
FBN1-EIF3B-20-GRAQ 20 (40 μL) 200 μL
FBN1-EIF3B-20-AQRE 20 (40 μL) 200 μL
FBN1-EIF3B-20-AQOR 20 (40 μL) 200 μL
FBN1-EIF3B-20-AQGO 20 (40 μL) 200 μL
FBN1-EIF3B-20-AQGR 20 (40 μL) 200 μL
FBN1-EIF3B-20-AQAQ 20 (40 μL) 200 μL

FBN1 Gene Summary

This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. [provided by RefSeq, Apr 2016]

Gene Name: Fibrillin 1

Chromosome: CHR15: 48700502 -48937985

Locus: 15q21.1

EIF3B Gene Summary

The Eukaryotic Translation Initiation Factor 3 Subunit B (EIF3B) gene is located on chr7 :2394473-2420377 at 7p22.3.

Gene Name: Eukaryotic Translation Initiation Factor 3 Subunit B

Chromosome: CHR7: 2394473 -2420377

Locus: 7p22.3

Gene Diseases

The FBN1 EIF3B Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.