FBXO16-ADAM32 Fusion FISH Probe
The FBXO16-ADAM32 Fusion FISH Probe is used to confirm a fusion of the FBXO16 and ADAM32 genes. The fusion of the FBXO16 and ADAM32 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FBXO16-ADAM32-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-RERE | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-REOR | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-REGO | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-REGR | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-REAQ | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-ORRE | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-OROR | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-ORGO | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-ORAQ | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-GORE | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-GOOR | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-GOGO | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-GOGR | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-GOAQ | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-GRRE | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-GROR | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-GRGO | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-GRGR | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-GRAQ | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-AQRE | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-AQOR | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-AQGO | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-AQGR | 20 (40 μL) | 200 μL |
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| FBXO16-ADAM32-20-AQAQ | 20 (40 μL) | 200 μL |
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FBXO16 Gene Summary
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Name: F-box Protein 16
Chromosome: CHR8: 28285928 -28347784
Locus: 8p21.1
ADAM32 Gene Summary
This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
Gene Name: ADAM Metallopeptidase Domain 32
Chromosome: CHR8: 38965049 -39142436
Locus: 8p11.22
Gene Diseases
The FBXO16 ADAM32 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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