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FBXO42-SPATA21 Fusion FISH Probe

The FBXO42-SPATA21 Fusion FISH Probe is used to confirm a fusion of the FBXO42 and SPATA21 genes. The fusion of the FBXO42 and SPATA21 genes has been associated with Bladder Urothelial Carcinoma, and Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FBXO42-SPATA21-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
FBXO42-SPATA21-20-RERE 20 (40 μL) 200 μL
FBXO42-SPATA21-20-REOR 20 (40 μL) 200 μL
FBXO42-SPATA21-20-REGO 20 (40 μL) 200 μL
FBXO42-SPATA21-20-REGR 20 (40 μL) 200 μL
FBXO42-SPATA21-20-REAQ 20 (40 μL) 200 μL
FBXO42-SPATA21-20-ORRE 20 (40 μL) 200 μL
FBXO42-SPATA21-20-OROR 20 (40 μL) 200 μL
FBXO42-SPATA21-20-ORGO 20 (40 μL) 200 μL
FBXO42-SPATA21-20-ORAQ 20 (40 μL) 200 μL
FBXO42-SPATA21-20-GORE 20 (40 μL) 200 μL
FBXO42-SPATA21-20-GOOR 20 (40 μL) 200 μL
FBXO42-SPATA21-20-GOGO 20 (40 μL) 200 μL
FBXO42-SPATA21-20-GOGR 20 (40 μL) 200 μL
FBXO42-SPATA21-20-GOAQ 20 (40 μL) 200 μL
FBXO42-SPATA21-20-GRRE 20 (40 μL) 200 μL
FBXO42-SPATA21-20-GROR 20 (40 μL) 200 μL
FBXO42-SPATA21-20-GRGO 20 (40 μL) 200 μL
FBXO42-SPATA21-20-GRGR 20 (40 μL) 200 μL
FBXO42-SPATA21-20-GRAQ 20 (40 μL) 200 μL
FBXO42-SPATA21-20-AQRE 20 (40 μL) 200 μL
FBXO42-SPATA21-20-AQOR 20 (40 μL) 200 μL
FBXO42-SPATA21-20-AQGO 20 (40 μL) 200 μL
FBXO42-SPATA21-20-AQGR 20 (40 μL) 200 μL
FBXO42-SPATA21-20-AQAQ 20 (40 μL) 200 μL

FBXO42 Gene Summary

Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Dec 2010]

Gene Name: F-box Protein 42

Chromosome: CHR1: 16576558 -16678948

Locus: 1p36.13

SPATA21 Gene Summary

The Spermatogenesis Associated 21 (SPATA21) gene is located on chr1 :16725137-16763919 at 1p36.13.

Gene Name: Spermatogenesis Associated 21

Chromosome: CHR1: 16725137 -16763919

Locus: 1p36.13

Gene Diseases

The FBXO42 SPATA21 Fusion has been associated with the following diseases:

Disease Name
Bladder Urothelial Carcinoma
Uterine Carcinosarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.