FLNA-MTCP1NB Fusion FISH Probe
The FLNA-MTCP1NB Fusion FISH Probe is used to confirm a fusion of the FLNA and MTCP1NB genes. The fusion of the FLNA and MTCP1NB genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FLNA-MTCP1NB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-RERE | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-REOR | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-REGO | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-REGR | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-REAQ | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-ORRE | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-OROR | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-ORGO | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-ORAQ | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-GORE | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-GOOR | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-GOGO | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-GOGR | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-GOAQ | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-GRRE | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-GROR | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-GRGO | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-GRGR | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-GRAQ | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-AQRE | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-AQOR | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-AQGO | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-AQGR | 20 (40 μL) | 200 μL |
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| FLNA-MTCP1NB-20-AQAQ | 20 (40 μL) | 200 μL |
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FLNA Gene Summary
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
Gene Name: Filamin A
Chromosome: CHRX: 153576899 -153603006
Locus: Xq28
Gene Diseases
The FLNA MTCP1NB Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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