FNBP4-INSL3 Fusion FISH Probe
The FNBP4-INSL3 Fusion FISH Probe is used to confirm a fusion of the FNBP4 and INSL3 genes. The fusion of the FNBP4 and INSL3 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FNBP4-INSL3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| FNBP4-INSL3-20-AQAQ | 20 (40 μL) | 200 μL |
|
INSL3 Gene Summary
This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
Gene Name: Insulin Like 3
Chromosome: CHR19: 17927321 -17932320
Locus: 19p13.11
FNBP4 Gene Summary
This gene encodes a protein containing two tryptophan-rich WW domains that binds the proline-rich formin homology 1 domains of formin family proteins, suggesting a role in the regulation of cytoskeletal dynamics during cell division and migration. It also binds intersectin family proteins suggesting a role in the maintenance of membrane curvature at sites of nascent vesicle formation. Naturally occurring mutations in this gene are associated with Waardenburg anophthalmia syndrome. [provided by RefSeq, Apr 2017]
Gene Name: Formin Binding Protein 4
Chromosome: CHR11: 47738068 -47788993
Locus: 11p11.2
Gene Diseases
The FNBP4 INSL3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|