GCFC1-TP53I3 Fusion FISH Probe
The GCFC1-TP53I3 Fusion FISH Probe is used to confirm a fusion of the GCFC1 and TP53I3 genes. The fusion of the GCFC1 and TP53I3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GCFC1-TP53I3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-RERE | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-REOR | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-REGO | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-REGR | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-REAQ | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-ORRE | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-OROR | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-ORGO | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-ORAQ | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-GORE | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-GOOR | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-GOGO | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-GOGR | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-GOAQ | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-GRRE | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-GROR | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-GRGO | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-GRGR | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-GRAQ | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-AQRE | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-AQOR | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-AQGO | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-AQGR | 20 (40 μL) | 200 μL |
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| GCFC1-TP53I3-20-AQAQ | 20 (40 μL) | 200 μL |
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TP53I3 Gene Summary
The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Gene Name: Tumor Protein P53 Inducible Protein 3
Chromosome: CHR2: 24300302 -24308085
Locus: 2p23.3
Gene Diseases
The GCFC1 TP53I3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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