GNL3L-XAGE3 Fusion FISH Probe
The GNL3L-XAGE3 Fusion FISH Probe is used to confirm a fusion of the GNL3L and XAGE3 genes. The fusion of the GNL3L and XAGE3 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GNL3L-XAGE3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-RERE | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-REOR | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-REGO | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-REGR | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-REAQ | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-ORRE | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-OROR | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-ORGO | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-ORAQ | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-GORE | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-GOOR | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-GOGO | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-GOGR | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-GOAQ | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-GRRE | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-GROR | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-GRGO | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-GRGR | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-GRAQ | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-AQRE | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-AQOR | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-AQGO | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-AQGR | 20 (40 μL) | 200 μL |
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| GNL3L-XAGE3-20-AQAQ | 20 (40 μL) | 200 μL |
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GNL3L Gene Summary
The protein encoded by this gene appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]
Gene Name: G Protein Nucleolar 3 Like
Chromosome: CHRX: 54556643 -54593720
Locus: Xp11.22
XAGE3 Gene Summary
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5' UTR. [provided by RefSeq, Jul 2008]
Gene Name: X Antigen Family Member 3
Chromosome: CHRX: 52891557 -52897119
Locus: Xp11.22
Gene Diseases
The GNL3L XAGE3 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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