GOSR1-JUP Fusion FISH Probe
The GOSR1-JUP Fusion FISH Probe is used to confirm a fusion of the GOSR1 and JUP genes. The fusion of the GOSR1 and JUP genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GOSR1-JUP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-RERE | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-REOR | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-REGO | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-REGR | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-REAQ | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-ORRE | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-OROR | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-ORGO | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-ORAQ | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-GORE | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-GOOR | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-GOGO | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-GOGR | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-GOAQ | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-GRRE | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-GROR | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-GRGO | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-GRGR | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-GRAQ | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-AQRE | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-AQOR | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-AQGO | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-AQGR | 20 (40 μL) | 200 μL |
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| GOSR1-JUP-20-AQAQ | 20 (40 μL) | 200 μL |
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JUP Gene Summary
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]
Gene Name: Junction Plakoglobin
Chromosome: CHR17: 39910858 -39942964
Locus: 17q21.2
GOSR1 Gene Summary
This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Golgi SNAP Receptor Complex Member 1
Chromosome: CHR17: 28804425 -28853832
Locus: 17q11.2
Gene Diseases
The GOSR1 JUP Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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